What is Semaglutide?
Semaglutide belongs to a class of medications known as glucagon-like peptide-1 receptor agonists, or GLP-1 RAs. It mimics the GLP-1 hormone, released in the gut in response to eating.
One role of GLP-1 is to prompt the body to produce more insulin, which reduces blood sugar (glucose). For that reason, health care providers have used semaglutide for more than 15 years to treat Type 2 diabetes.
But GLP-1 also interacts with the parts of the brain that suppress your appetite and signal you to feel full. When used in conjunction with diet and exercise, it can cause significant weight loss — and a reduced risk of cancer, diabetes and heart disease — in people who are obese or overweight.
Why use Semaglutide medication for weight loss?
Here are some reasons why semaglutide may be used for weight loss:
Appetite Suppression: semaglutide appears to reduce appetite, leading to decreased food intake. This effect can contribute to weight loss, as individuals consume fewer calories.
Improved Insulin Sensitivity: By improving insulin sensitivity, semaglutide may help the body utilize glucose more effectively. This can have positive effects on metabolism and contribute to weight loss.
Slowed Gastric Emptying: semaglutide slows down the rate at which the stomach empties, leading to a feeling of fullness for a longer period. This can help individuals eat smaller portions and reduce overall calorie intake.
Caloric Expenditure: Some research suggests that semaglutide may increase energy expenditure, potentially contributing to weight loss.
Is there a required BMI to qualify for semaglutide medication?
The minimum BMI to qualify for semaglutide treatment is 25 or higher.
How do I know if I am eligible for semaglutide?
During your in initial in-office consultation with Dr. Gupta, you will thoroughly review all medical information and discuss your eligibility for a personalized semaglutide treatment plan.
How long will I need to stay on medication?
The duration for which individuals stay on semaglutide can vary based on individual factors, including the person's response to the medication, their weight management goals, and their overall health. Typically, Dr. Gupta will assess the progress of each patient periodically and make decisions about continuing or discontinuing the medication based on individual response.
How much weight can I expect to lose?
Studies show that individuals on weekly GLP-1 injections on average (semaglutide and tirzepatide study numbers) lose 12-15% body weight after one year at the full-dose. Individual results do vary, and concurrent lifestyle modifications can have a big impact. Studies also indicate that a mere 5% reduction in weight can significantly enhance conditions such as hypertension, cholesterol levels, cardiovascular diseases, PCOS, osteoarthritis, and more.
Citation- Shi Q, Wang Y, Hao Q, et al. Pharmacotherapy for adults with overweight and obesity: a systematic review and network meta-analysis of randomized controlled trials. Lancet. 2022;399:259-269.
What if side effects occur?
At Gupta Plastic Surgery, you will undergo multiple consultations with Dr. Gupta at crucial junctures to identify the safest and most effective medication dosage for you. Throughout these consultations, Dr. Gupta will closely monitor your response to ensure that the medication is effectively addressing your needs. Many side effects can be easily managed and only in rare instances does treatment need to be stopped.
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What is the best time to take your semaglutide medication?
Administer medication once weekly on the same day each week, at any time of the day, with or without meals.
Does my semaglutide medication need to be refrigerated?
This medication was designed to be unrefrigerated for shipment and has been tested to be stable in extreme temperatures, however it should be kept inside your refrigerator in the refrigerator-safe pouch provided to you, to ensure longevity and freshness of the product.
Do I need to get lab work done?
At Gupta Plastic Surgery your well-being takes precedence in the prescription of semaglutide medication. We uphold a critical standard for patient care that we do not compromise on. This includes comprehensive lab work before initiating any semaglutide treatment. The results of laboratory tests assist us in assessing whether semaglutide aligns with the specific requirements of your body.
What kind of bloodwork do I need?
Dr. Gupta will vigilantly oversee essential indicators, such as Complete Blood Count, Complete Metabolic Panel, lipids (cholesterol and triglycerides), TSH, and HbA1c. This thorough monitoring aims to detect any potential underlying liver, pancreatic, kidney and thyroid dysfunction before initiating, and during treatment.
How long will it take for my results?
It takes approximately 2-3 days after your scheduled visit for us to receive your results. Dr. Gupta will then review your results with you to start your weight loss journey.
Where do I get my bloodwork done?
Our collaboration with Quest Diagnostics across the country has simplified the process for you. Once your lab work is requested, we will alert you and provide a convenient link. You can easily schedule appointments at your convenience through Quest. This is to be done every 6 months.
Why do some companies not require bloodwork?
There are many online providers that are cutting corners and not meeting the standard of care. We firmly believe in the principle of first do no harm and thoroughly screen each individual to rule out possible reasons where semaglutide therapy might be contraindicated.
What is HbA1c and why is it tested?
HbA1c is short for Glycated Hemoglobin.
The HbA1c test measures the average blood sugar levels over a period of time and is primarily used to assess diabetes management. It provides a long-term picture of your blood sugar control and helps monitor the risk of complications associated with diabetes.
What is TSH and why is it tested?
TSH stands for Thyroid Stimulating Hormone.
The TSH test measures the levels of thyroid-stimulating hormone, which is crucial for evaluating thyroid function. Abnormal TSH levels can indicate an underactive or overactive thyroid, which can impact your metabolism, energy levels, and overall well-being.
What are Lipids and why are they tested?
Lipids play various roles, including energy storage, insulation, and hormone production. Lipid tests, such as HDL (high-density lipoprotein), LDL (low-density lipoprotein), total cholesterol, and triglycerides, provide valuable information about an individual's cardiovascular health.
What is CMP and why is it tested?
The comprehensive metabolic panel (CMP).
The CMP test assesses different markers related to your body's metabolism, including liver function, kidney function, blood sugar levels, and electrolyte balance. It can provide insights into conditions like liver or kidney disease, diabetes, and electrolyte imbalances.
What is CBC and why is it tested?
A complete blood count (CBC).
The CBC test measures various components of your blood, such as red blood cells, white blood cells, and platelets. It can help detect conditions like anemia, infections, and blood disorders.
How do I get started?
Get ready to begin your journey towards a healthier, happier you by completing the medical intake form today. Simply click on the "Get Started" link to get going then call us to schedule your initial consultation with Dr. Gupta.
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Who do I contact for missing communication or questions?
For assistance, please reach out to our Gupta Plastic Surgery team at (858) 408-6100.
What forms of payment do you accept?
We accept cash, Visa, Mastercard, Discover and American Express. Please note, we do not accept personal checks, gift or pre-loaded credit cards or FSA/HSA cards.